Trough Imatinib Plasma Levels

Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia Picard S, Titier K, Etienne G, et al. Blood. [...]

Imatinib Pharmacokinetics

Imatinib pharmacokinetics and its correlation with response plasma exposure of imatinib and its correlation with clinical response in the tyrosine kinase inhibitor optimization and selectivity [...]

Plasma Exposure of Imatinib

Plasma exposure of imatinib and its correlation with clinical response in the tyrosine kinase inhibitor optimization and selectivity trial.  Guilhot F, Hughes TP, Cortes J, et al. Haematologica. [...]

Imatinib Plasma Levels

Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors. Demetri GD, Wang Y, Wehrle E, et al. J Clin [...]

Therapeutic Drug Monitoring of Imatinib in Chronic Myeloid Leukemia

Therapeutic drug monitoring of imatinib in chronic myeloid leukemia: experience from 1216 patients at a centralized laboratory. Bouchet S, Titier K, Moore N, et al. Fundam Clin Pharmacol. [...]

Personalized Daily Doses of Imatinib by Therapeutic Drug Monitoring

Personalized daily doses of imatinib by therapeutic drug monitoring increase the rates of molecular responses in patients with chronic myeloid leukemia. Final results of the randomized OPTIM [...]