MyCare Psychiatry
All tests CE marked with applications on major clinical chemistry analysers:
- Clozapine
- Total Risperidone / Paliperidone
- Total Aripiprazole
- Quetiapine
- Olanzapine
The MyCare Psychiatry TDM assays provide quantitative insights for six of the most commonly prescribed antipsychotic drugs.
These assays can significantly improve the turnaround time of test results, provide objective information, and when used in combination with other clinical information, lead to better-informed treatment decisions.
Clozapine
Antipsychotic Product Performance
| Assay Range ng / mL | Within-Laboratory Precision, %CV | Method Comparison to LC-MS/MS | ||||
| Low Control | Medium Control | High Control | Slope | Intercept | Correlation Coefficient | |
| 68 – 1500 | 5.4 | 4.4 | 4.5 | 1.037 | -27.8 | 0.9269 |
Recommended therapeutic reference ranges, laboratory alert levels and levels of recommendation for therapeutic drug monitoring*
| Level | Therapeutic reference range (ng/mL) | Laboratory alert level (ng/mL) |
| 1 | 350-600 | 1000 |
Total Risperidone
Measures both Risperidone and Paliperidone
Antipsychotic Product Performance
| Assay Range ng / mL | Within-Laboratory Precision, %CV | Method Comparison to LC-MS/MS | ||||
| Low Control | Medium Control | High Control | Slope | Intercept | Correlation Coefficient | |
| 16 – 120 | 3.7 | 2.8 | 3.3 | 0.98 | 1.23 | 0.96 |
Recommended therapeutic reference ranges, laboratory alert levels and levels of recommendation for therapeutic drug monitoring*
| Level | Therapeutic reference range (ng/mL) | Laboratory alert level (ng/mL) |
| 2 | 20 – 60 | 120 |
Total Aripiprazole
Antipsychotic Product Performance
| Assay Range ng / mL | Within-Laboratory Precision, %CV | Method Comparison to LC-MS/MS | ||||
| Low Control | Medium Control | High Control | Slope | Intercept | Correlation Coefficient | |
| 45 – 1000 | 8.3 | 4.0 | 3.9 | 1.01 | 2.56 | 0.98 |
Recommended therapeutic reference ranges, laboratory alert levels and levels of recommendation for therapeutic drug monitoring*
| Level | Therapeutic reference range (ng/mL) | Laboratory alert level (ng/mL) |
| 2 | 150 – 500 | 1000 |
Quetiapine
Antipsychotic Product Performance
| Assay Range ng / mL | Within-Laboratory Precision, %CV | Method Comparison to LC-MS/MS | ||||
| Low Control | Medium Control | High Control | Slope | Intercept | Correlation Coefficient | |
| 34 – 700 | 7.4 | 3.7 | 3.7 | 1.03 | 13.55 | 0.92 |
Recommended therapeutic reference ranges, laboratory alert levels and levels of recommendation for therapeutic drug monitoring*
| Level | Therapeutic reference range (ng/mL) | Laboratory alert level (ng/mL) |
| 2 | 20 – 60 | 120 |
Olanzapine
Antipsychotic Product Performance
| Assay Range ng / mL | Within-Laboratory Precision, %CV | Method Comparison to LC-MS/MS | ||||
| Low Control | Medium Control | High Control | Slope | Intercept | Correlation Coefficient | |
| 22 – 114 | 4.6 | 1.9 | 3.7 | 1.038 | -0.1 | 0.98 |
Recommended therapeutic reference ranges, laboratory alert levels and levels of recommendation for therapeutic drug monitoring*
| Level | Therapeutic reference range (ng/mL) | Laboratory alert level (ng/mL) |
| 1 | 20 – 80 | 100 |
